🔬Absorption

Black Pepper Extract

Black Pepper Extract (Piperine) significantly enhances the bioavailability and absorption of other supplement ingredients.

Clinical Dose: 5mgFound in: 40 products

What Does Black Pepper Extract Do?

Black pepper extract, specifically its active component piperine, acts as a metabolic gatekeeper in your pre-workout. While it doesn't provide energy or pumps directly, it ensures that the other ingredients in your scoop actually make it into your bloodstream rather than being wasted by your digestive system. It is the ultimate "support" ingredient for any high-performance stack.

  • Enhanced Bioavailability: Piperine inhibits specific enzymes like CYP3A4 and transporters like P-glycoprotein in the liver and gut that would otherwise break down supplements before they can be absorbed.
  • Synergistic Potentiation: It is famous for its ability to increase the absorption of certain compounds, such as curcumin or CoQ10, by massive margins, ensuring you get the full value of your supplement stack.
  • Thermogenic Stimulus: By slightly increasing the internal temperature of the body through thermogenesis, it may improve the rate at which nutrients are transported across the intestinal wall.
  • Enzyme Regulation: It modulates the metabolic pathway of various amino acids and water-soluble vitamins, keeping them active in your system for longer durations by slowing their excretion.

Clinical vs. Gym Bro Dosing

TierDoseNotes
Threshold2 mgThe bare minimum found in budget-friendly formulas to claim absorption benefits.
Clinical5 mgThe gold standard dose used in most clinical trials and premium products.
High Performance10 mgFound in 'loaded' pre-workouts to maximize the uptake of high-dose ingredients.

Key Insight: The quality of the extract matters more than the raw weight. Always look for labels that specify a 95% Piperine standardization or use the trademarked BioPerine version. At the recommended 5 mg dose, you are hitting the sweet spot for maximum absorption without risking stomach irritation.

Side Effects & Warnings

  • Digestive Warmth: Some users report a mild 'spicy' or warm sensation in the stomach shortly after ingestion, which is typical for pepper derivatives.
  • Gastrointestinal Upset: In rare cases or at very high doses, it may cause minor cramping or heartburn, especially if you have a sensitive stomach or are training on an empty stomach.
  • Medication Interaction: Because piperine slows the breakdown of many substances, it can unintentionally increase the potency and blood concentration of certain prescription medications.

Contraindications: If you are taking any prescription pharmaceuticals, especially blood thinners or anticonvulsants, consult your physician before using products containing black pepper extract, as it can significantly alter how your body processes those drugs.