Grapefruit Extract

What Does Grapefruit Extract Do?

Grapefruit extract is a potent metabolic modulator used in pre-workouts primarily to slow down the breakdown of other stimulants and performance enhancers. It works by inhibiting specific enzymes in the liver and intestines, effectively keeping active ingredients in your bloodstream for longer periods than they would naturally stay.

• Enhanced Bioavailability: It inhibits the CYP3A4 enzyme, which is responsible for metabolizing many supplements, allowing more of the active compound to reach systemic circulation.
• Prolonged Energy: By slowing the degradation of caffeine and other stimulants, it helps prevent the "crash" and extends the duration of the energy boost.
• Synergistic Potency: It acts as a force multiplier, making smaller doses of other ingredients feel more impactful by preventing their rapid excretion.
• Antioxidant Support: Rich in naringin and naringenin, it provides cellular protection against oxidative stress induced by intense training sessions.

Clinical vs. Gym Bro Dosing

Key Insight: Because grapefruit extract alters how your body processes chemicals, it is most effective when paired with stimulants like caffeine or exotic fat burners. However, you should never exceed the recommended dose as it can lead to over-stimulation by preventing your body from clearing stimulants at a normal rate.

Side Effects & Warnings

• Over-Stimulation: Because it keeps caffeine in your system longer, you might experience jitters, insomnia, or an elevated heart rate if your pre-workout is high-stim.
• Digestive Sensitivity: Some users may experience mild stomach upset or acidity if taken on an empty stomach due to the extract's natural properties.

Contraindications: This is the most important warning: Grapefruit extract interacts with a wide range of prescription medications (including statins and blood pressure meds). If you are on any medication, consult a doctor before using a supplement containing this ingredient.