Resveratrol

What Does Resveratrol Do?

Resveratrol is a polyphenolic compound primarily found in grape skins and berries, acting as a powerful cellular guardian. In the world of sports nutrition, it is prized for its ability to mitigate the oxidative damage caused by intense physical exertion, allowing you to push harder while protecting your long-term health.

• Reduced Oxidative Stress: It neutralizes free radicals produced during heavy lifting, which prevents cellular damage and supports faster recovery between sets.
• Mitochondrial Biogenesis: Resveratrol is known to activate SIRT1, a pathway that stimulates the production of new mitochondria, potentially increasing your aerobic capacity and energy efficiency.
• Nitric Oxide Enhancement: It supports the health of the endothelium, the lining of your blood vessels, which can lead to better vasodilation and improved nutrient delivery to muscles.
• Anti-Inflammatory Support: By modulating the body's inflammatory response, it helps manage the systemic stress of high-volume training blocks.

Clinical vs. Gym Bro Dosing

Key Insight: While the recommended dosage in some databases is listed at 0.00mg due to its rarity in pre-workouts, clinical research suggests that 250mg to 500mg is the sweet spot for performance. Be aware that taking massive doses immediately after training might actually dampen the natural inflammatory signals your body needs to trigger muscle growth, so it is best used as a pre-workout protector.

Side Effects & Warnings

• Gastrointestinal Issues: Doses exceeding 1,000mg may cause mild nausea, gas, or diarrhea in sensitive individuals.
• Blood Thinning Effects: Resveratrol has mild anticoagulant properties, which may increase the risk of bruising or bleeding if combined with certain medications.
• Hormetic Blunting: Excessive antioxidant intake can theoretically interfere with the "good" stress signals that trigger muscle adaptation if taken in extreme quantities.

Contraindications: Avoid high-dose resveratrol if you are currently prescribed blood thinners (like Warfarin) or NSAIDs without consulting your doctor first, as it may enhance their effects.