L Glutathione Reduced

What Does L-Glutathione Reduced Do?

L-Glutathione is often referred to as the body's "master antioxidant." In the context of a pre-workout, the reduced form is used to combat the oxidative stress generated during high-intensity training, facilitating faster adaptation and recovery.

• Oxidative Stress Reduction: It directly neutralizes reactive oxygen species (ROS), protecting muscle cells from the damage that occurs during heavy lifting.
• Nitric Oxide Potentiation: When combined with L-Citrulline, it helps prevent the breakdown of nitric oxide, leading to longer-lasting muscle pumps and better nutrient delivery.
• Enhanced Recovery: By mitigating the inflammatory response immediately after exercise, it helps reduce delayed onset muscle soreness (DOMS) and systemic fatigue.
• Cellular Adaptation: It supports the body’s ability to adapt to training stimuli by maintaining a healthy redox balance within the muscle tissue, ensuring you're ready for your next session.

Clinical vs. Gym Bro Dosing

Key Insight: While 250mg is the recommended clinical dose for recovery, the real magic happens when you stack L-Glutathione with 2-8g of L-Citrulline. Research suggests this specific combination sustains nitric oxide levels significantly longer than taking Citrulline alone, extending your pump well into the post-workout window.

Side Effects & Warnings

• Digestive Issues: Some users may experience mild stomach upset, bloating, or cramping, especially if taken on an empty stomach.
• Sulfur Smell: Because glutathione contains sulfur, high doses can occasionally cause a temporary sulfurous odor in breath or sweat.
• Zinc Interference: Chronic, very high-dose supplementation (over 1,000mg) may potentially impact zinc absorption over time.

Tip: Always ensure you are using the "reduced" form of L-Glutathione. The non-reduced (oxidized) form is poorly absorbed by the human digestive tract, making it largely ineffective for performance purposes. Look for branded versions like Setria for maximum bioavailability.