🔬Vitamins & Minerals

Magnesium Glycinate

Magnesium glycinate is an essential mineral crucial for numerous bodily functions, including muscle and nerve function, supporting overall health.

Clinical Dose: 500mgFound in: 17 products

What Does Magnesium Glycinate Do?

Magnesium glycinate is a highly bioavailable form of magnesium chelated with the amino acid glycine, making it significantly more effective for athletes than cheaper, poorly absorbed salts like magnesium oxide. In a performance context, it serves as a critical regulator of muscle contraction and energy metabolism, ensuring your nervous system and muscle fibers communicate efficiently.

  • Muscle Relaxation & Cramp Prevention: Magnesium regulates calcium transport across cell membranes; by counteracting calcium's role in muscle contraction, it allows fibers to relax, effectively preventing the painful cramping that ruins high-volume sets.
  • ATP Energy Production: Magnesium is a mandatory cofactor for the enzyme ATP synthase. You cannot effectively convert the food you eat or the glycogen you store into cellular energy (ATP) without sufficient magnesium levels.
  • Enhanced Recovery & Sleep: The glycine component acts as an inhibitory neurotransmitter, which helps lower cortisol levels and promotes the deep, restorative sleep necessary for protein synthesis and tissue repair.
  • Improved Insulin Sensitivity: Magnesium plays a vital role in glucose metabolism, helping your body shuttle carbohydrates into muscle cells more effectively for better pumps and sustained endurance.

Clinical vs. Gym Bro Dosing

TierDoseNotes
Maintenance100-200mgSufficient for sedentary individuals to avoid deficiency.
Clinical Standard300-400mgThe standard RDA for active adults to support general health.
Performance Dose500mgThe sweet spot for heavy lifters to optimize recovery and nerve function.
High Performance600mg+Used by elite endurance athletes to replace massive sweat losses.

Key Insight: To maximize the benefits of magnesium glycinate, take it in the evening or post-workout. Unlike magnesium citrate or oxide, which often cause a laxative effect, the glycinate form is absorbed through different pathways in the gut, ensuring the mineral actually reaches your muscle tissue rather than causing digestive distress.

Side Effects & Warnings

  • Mild Drowsiness: Due to the calming effect of glycine on the central nervous system, some users may feel a bit too relaxed if taken immediately before a high-intensity session.
  • Digestive Tolerance: While it is the gentlest form of magnesium, exceeding 600mg in a single sitting may still cause mild stomach upset or loose stools in sensitive individuals.
  • Blood Pressure Interaction: Magnesium acts as a natural vasodilator. While usually beneficial, it may cause slight lightheadedness if you already have very low blood pressure or are taking prescription vasodilators.

Tip: If you find that magnesium glycinate makes you feel lethargic during your workout, check your pre-workout label. If it's included there, ensure you are also consuming adequate sodium to maintain the necessary electrolyte pressure for explosive movements.