🧠Focus

Acetyl-l-carnitine

Acetyl-L-carnitine crosses the blood-brain barrier to enhance cognitive function and focus.

Clinical Dose: 1gFound in: 119 products

What Does Acetyl-L-Carnitine Do?

Acetyl-L-Carnitine (ALCAR) is a highly bioavailable form of L-carnitine that uniquely crosses the blood-brain barrier, making it a premier choice for cognitive enhancement in pre-workout formulas. While standard carnitine focuses on fat metabolism, ALCAR prioritizes mental performance and neurological health.

  • Enhanced Mental Focus: By donating acetyl groups to facilitate the production of acetylcholine—a key neurotransmitter—ALCAR sharpens your concentration and mind-muscle connection during heavy sets.
  • Mitochondrial Energy Support: It assists in transporting long-chain fatty acids into the mitochondria, where they are oxidized for cellular energy (ATP), fueling both your brain and muscles.
  • Neuroprotective Properties: ALCAR acts as a potent antioxidant within the brain, helping to mitigate oxidative stress and protect neurons from damage caused by high-intensity training.
  • Reduced Mental Fatigue: It helps maintain cognitive clarity and prevents the "brain fog" that often sets in during the latter half of a grueling workout session.

Clinical vs. Gym Bro Dosing

TierDoseNotes
Threshold500mgMinimum effective dose for general cognitive support.
Clinical1,000mgThe gold standard for noticeable focus and performance.
Performance1,500mgHigh-end dose for maximum mental clarity and drive.
Upper Limit2,000mgMaximum recommended daily intake; diminishing returns beyond this.

Key Insight: To get the most out of Acetyl-L-Carnitine, aim for the 1,000mg clinical dose. It is best taken 30-60 minutes before training to allow the ingredient to cross the blood-brain barrier and begin supporting neurotransmitter synthesis.

Side Effects & Warnings

  • Digestive Upset: Some users may experience mild nausea, stomach cramps, or diarrhea, particularly when taking higher doses on an empty stomach.
  • Insomnia or Restlessness: Due to its ability to increase alertness and mental energy, taking ALCAR late in the evening may interfere with your ability to fall asleep.
  • Fishy Odor: In rare cases, high doses of carnitine supplements can cause a slight "fishy" smell in sweat or breath as the body breaks it down.

Tip: If you have a sensitive stomach, try taking your pre-workout containing ALCAR with a small piece of fruit rather than on a completely empty stomach to mitigate potential digestive discomfort.