💪Pump

nitrosigine

Nitrosigine enhances nitric oxide production, leading to increased vasodilation and improved blood flow to muscles.

Clinical Dose: 1.5gFound in: 94 products

What Does Nitrosigine Do?

Nitrosigine is a patented complex of bonded arginine silicate that significantly boosts nitric oxide levels more effectively than standard L-arginine. It works by increasing blood flow and arterial diameter, ensuring your muscles receive a surge of oxygen and nutrients during intense training sessions.

  • Enhanced Vasodilation: By increasing nitric oxide production, it relaxes blood vessels, leading to skin-splitting pumps and improved vascularity during your sets.
  • Extended Duration: Unlike standard arginine, Nitrosigine has been shown to stay in the system for up to six hours, providing sustained blood flow long after your workout ends.
  • Cognitive Support: Research suggests it can improve mental focus and processing speed, making it a dual-threat for both physical and mental performance.
  • Muscle Recovery: Improved blood flow facilitates the removal of metabolic waste products like lactate, potentially reducing post-workout soreness.
  • High Bioavailability: It is engineered to bypass the digestive issues and poor absorption rates typically associated with traditional arginine supplements.

Clinical vs. Gym Bro Dosing

TierDoseNotes
Threshold500mgMinimum dose to see slight improvements in blood flow.
Standard1,000mgCommon in multi-ingredient blends; effective for moderate pumps.
Clinical1,500mgThe gold standard dose used in most human clinical trials.
Max Performance2,000mgUpper limit for extreme vasodilation; often stacked with Citrulline.

Key Insight: To maximize the "pump" effect, take Nitrosigine approximately 30-45 minutes before your workout. Because it is highly bioavailable, you do not need the massive 6-10g doses required by L-Citrulline to achieve similar nitric oxide spikes, though they are often stacked together for synergistic effects.

Side Effects & Warnings

  • Low Blood Pressure: Because it acts as a potent vasodilator, those with naturally low blood pressure might experience slight lightheadedness or dizziness.
  • Digestive Comfort: Nitrosigine is generally much easier on the stomach than Arginine HCL, but sensitive users may still experience mild bloating at very high doses.
  • Headaches: Increased blood flow to the brain can occasionally trigger minor headaches in individuals sensitive to nitric oxide boosters.

Tip: Nitrosigine is entirely non-stimulant, making it an excellent addition to late-night workouts where you want the performance benefits without the insomnia associated with caffeine or other stimulants.