Hordenine
Hordenine is a mild stimulant that can enhance energy levels and support fat metabolism.
What Does Hordenine Do?
Hordenine is a naturally occurring alkaloid found in barley and various cacti that functions as a mild central nervous system stimulant. While it provides a subtle kick on its own, its primary role in pre-workouts is to act as a metabolic gatekeeper, preventing the rapid breakdown of other mood-enhancing chemicals.
- Extended Energy: It acts as a selective MAO-B inhibitor, which slows down the degradation of phenylethylamine (PEA) and dopamine, keeping your energy levels stable for longer.
- Metabolic Boost: By stimulating the release of norepinephrine, hordenine helps mobilize fatty acids for energy, supporting fat loss during high-intensity cardio.
- Cognitive Focus: By preserving dopamine levels, it helps you maintain a "tunnel vision" focus throughout your training session, preventing mid-workout mental fatigue.
- Synergistic Potency: It enhances the effectiveness of caffeine and other stimulants, ensuring that the "hit" from your pre-workout lasts until your final rep.
Clinical vs. Gym Bro Dosing
| Tier | Dose | Notes |
|---|---|---|
| Threshold | 0.80 mg | The minimum level often found in basic stimulant complexes. |
| Moderate | 20 mg | A common entry-point for metabolic support. |
| Performance | 50 mg | The sweet spot for noticeable energy extension. |
| High Performance | 75 mg+ | For advanced users stacking multiple stimulants. |
Key Insight: Because hordenine is a "synergist," you don't need massive doses to feel it. Its main job is to make the other ingredients in your pre-workout work harder and longer, so look for it in formulas containing caffeine or synephrine.
Side Effects & Warnings
- Elevated Heart Rate: Like most stimulants, hordenine can cause a temporary increase in heart rate or palpitations.
- Blood Pressure: It may cause vasoconstriction, leading to a rise in blood pressure during exercise.
- Jitters: When combined with high doses of caffeine, it can lead to over-stimulation or "the jitters."
Contraindications: Avoid hordenine if you are currently taking prescribed MAOIs or have a history of cardiovascular issues. Always start with a half-scoop to assess your tolerance to the stimulant synergy.
Top Products Containing Hordenine
Sorted by popularity. Dosage shown per serving.
